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Christiane e. wobus

WebMar 1, 2007 · University of Michigan: Ann Arbor, MI, US. 2007-03-01 to present associate professor (Microbiology and Immunology) Employment. Show more detail. Source : … WebFeb 17, 2024 · Viruses interact with receptors on the cell surface to initiate and co-ordinate infection. The distribution of receptors on host cells can be a key determinant of viral tropism and host infection. Unravelling the complex nature of virus-receptor interactions is, therefore, of fundamental importance to understanding viral pathogenesis. Noroviruses are non …

Prolonged SARS-CoV-2 replication in an immunocompromised patient …

WebA.E. Fischer et al. / Journal of Virological Methods 213 (2015) 111–117 113 Fig. 1. Microfluidic system. (a) Droplet formation chips contain 3 inlet ports (one for oil/surfactant and two for aqueous solutions) and one outlet port for droplet collection. WebJanelle N Stokely, 1 Sandra Niendorf, 2 Stefan Taube, 1 Marina Hoehne, 2 Vincent B Young, 1,3 Mary AM Rogers, 4 Christiane E Wobus 1 1 Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA; 2 Department of Infectious Diseases, Consultant Laboratory for Noroviruses, Robert Koch Institute, Berlin, … hugo belanger https://eliastrutture.com

Christiane Wobus Publications University of Michigan

WebSep 22, 2024 · Viral cultures and sequence analysis demonstrate ongoing replication of infectious SARS-CoV-2 virus for at least 119 days. The patient had three admissions related to COVID-19 over a four-month period and was treated twice with remdesivir and convalescent plasma with resolution of symptoms. The patient’s lack of seroconversion … WebMar 7, 2003 · STAT1 –/– mice, like wild-type mice, contained MNV-1 genome in intestine, liver, and spleen one day after inoculation ( Fig. 4 D). In contrast to wild-type mice, STAT1 –/– mice had high levels of MNV-1 RNA in multiple organs, as well as substantial tissue pathology, 3 and 7 days after infection. ( Fig. 4, D and E). WebSnippet: The global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the associated disease COVID-19, requires therapeutic interventions that can be rapidly identified and translated to clinical care. Traditional drug discovery methods have a >90% failure rate and can take 10 to 15 y from target identification to clinical use. hugo bergmann gmbh

Christiane E Wobus - ResearchGate

Category:Murine Norovirus: a Model System To Study Norovirus Biology …

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Christiane e. wobus

Prolonged SARS-CoV-2 replication in an immunocompromised patient …

WebHere we show that epithelial non-canonical NFkB signaling mediated by NFkB-inducing kinase (NIK) is highly active in intestinal lymphoid follicles, and is required for M-cell maintenance. Intestinal NIK signaling modulates M-cell differentiation and elicits both local and systemic IL-17A and IgA production. Importantly, intestinal NIK signaling ... WebMar 12, 2024 · Descriptive statistics of Seahorse real-time ATP rate assay for RAW 264.7 cells infected with MNV for 8 h. 1 Mean of glycolysis-ATP in mock versus MNV infected is statistically significant with a P value of 0.0029 (2-way ANOVA with Tukey’s multiple-comparison test). 2 Mean of mitochondrial-ATP in mock versus MNV infected is …

Christiane e. wobus

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WebMar 1, 2007 · University of Michigan: Ann Arbor, MI, US. 2007-03-01 to present associate professor (Microbiology and Immunology) Employment. Show more detail. Source : Christiane Wobus. expand_more.

WebAU - Wobus, Christiane E. AU - Baric, Ralph S. AU - Virgin IV, Herbert W. PY - 2008/7. Y1 - 2008/7. N2 - Human noroviruses cause more than 90% of epidemic nonbacterial gastroenteritis. However, the role of B cells and antibody in the immune response to noroviruses is unclear. Previous studies have demonstrated that human norovirus … WebJul 31, 2024 · In vivo, MNV strains have two main infection phenotypes (Table 1).MNV-1 causes an acute infection, and infectious virus is cleared within 1 week ().Infection is initiated in the distal part of the small intestine and spreads from there to other sites in the small and large intestine, mesenteric lymph nodes, and spleen ().Replication at early times …

WebMar 1, 2024 · Disease progression during SARS-CoV-2 infection is tightly linked to the fate of lung epithelial cells, with severe cases of COVID-19 characterized by direct injury of the alveolar epithelium and an impairment in its regeneration from progenitor cells. The molecular pathways that govern respiratory epithelial cell death and proliferation during … WebAU - Wobus, Christiane E. AU - Baric, Ralph S. AU - Virgin IV, Herbert W. PY - 2008/7. Y1 - 2008/7. N2 - Human noroviruses cause more than 90% of epidemic nonbacterial …

WebAug 29, 2024 · They worked with co-corresponding authors Christiane E. Wobus, an associate professor of microbiology and immunology and J. Scott VanEpps, an assistant professor of emergency medicine, both at the U-M Medical School, as well as immunology PhD students Dylan Bartikofsky and Carmen Mirabelli, to test the coating against a wide …

WebFeb 19, 2024 · Pathogenic mechanisms underlying severe SARS-CoV2 infection remain largely unelucidated. High throughput sequencing technologies that capture genome and transcriptome information are key approaches to gain detailed mechanistic insights from infected cells. These techniques readily detect both pathogen and host-derived … blink johnson and johnsonWebChristiane E Wobus; Neutral red (NR) is a dye that must be actively imported into the cell, and, therefore, the dye has been used for decades to selectively stain living cells. In … blinken osa archívumWebChristiane E Wobus, Thanh H Nguyen. PMID: 22440967 DOI: 10.1016/j.coviro.2011.12.006 No abstract available. Publication types Editorial … bliss 48 vanity