Web本发明所述多肽，可以有效结合子宫内膜癌细胞中异常增多的突变型tp53，抑制smad3的磷 酸化 和子宫内膜癌生长，从而降低放疗剂量以及 化疗药物 的使用浓度，提高子宫内膜癌细胞的 放化疗 敏感性，且对正常细胞无明显 副作用 。 WebHighly specific and rigorously validated in-house, Phospho-Smad2 (Ser465/467) (138D4) Rabbit Monoclonal Antibody (CST #3108) is ready to ship. ... Smad2 and Smad3 become phosphorylated at their carboxy-termini (Ser465/467 on Smad2; Ser423/425 on Smad3) by the receptor kinase TGF-β R1 (9-11). Following phosphorylation, Smad2 and Smad3 …
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WebFeb 11, 2024 · 松果菊苷（上海融禾医药科技发展有限公司，纯度97%，批号：190906）；兔多克隆抗体TGF-β1（美国 Abcam 公司）；phospho-Smad2（p-Smad2,美国 CST 公司）；phospho-Smad3（p-Smad3, Bioss公司）；蛋白Marker（美国Thermo 公司）；Trizol 试剂（加拿大Roche 公司）；逆转录试剂盒（谷歌 ... WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-Smad3 antibody [EP568Y] (ab40854) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed specificity ...
WebSep 15, 2024 · Sequencings and proteomics revealed that YAP bound to Smad3 and promoted the proliferation of hBdSMC via MAPK/ERK signaling pathway in stiff ECM. Moreover, CUT and TAG sequencing and dual-luciferase assays demonstrated that Smad3 inhibited the transcription of JUN. The YAP inhibitor CA3 was used in a partial bladder … Web200 ul 3102S Smad2/3 Antibody 100 ul 9523S Smad3 (C67H9) Rabbit mAb 100 ul 9132S. Stat3 Antibody. 100 ul 9903S U0126 (MEK1/2 Inhibitor) 5 mg 2479S VEGF Receptor 2 (55B11) Rabbit mAb 100 ul 3932S. Vimentin (R28) Antibody. 100 ul. 二抗广州聚研CST 现货. 目录号 产品说明. 规格. 7076S Anti-mouse IgG, HRP-linked Antibody 1 ml 7074S
Web购买我公司生化试剂质量保证，价格实惠。872-50-4 1-甲基-2-吡咯烷酮 一旦售出，都有我司专业技术人员全程指导操作, 公司所售产品都为近期，订购。 中文名称：872-50-4 1-甲基-2-吡咯烷酮 其他中文名称： n-甲基吡咯烷酮；1-甲基吡咯烷酮；n-甲基-2-吡咯烷酮；nmp溶剂；二异丙基酮；n-甲基-α-吡咯烷酮 WebSep 1, 2024 · TGF-β1 causes cardiac fibrosis by stimulating Smad3 and PI3K-Akt-GSK-3β signaling pathways. TGF-β1 phosphorylates and activates the highly-conserved cytoplasmic proteins of the SMADs family, and PI3K-Akt-GSK-3β pathway, thereby regulating the expression of the related genes leading to fibrosis.
WebMar 19, 2024 · The protein expression levels of p-Smad2, p-Smad3, p-ERK, and p-JNK were detected after the treatment described above and, consistent with the above results, it was found that compared to the F 2 S 3 group, concomitant treatment with F 2 S 3 in the presence of human recombinant TGF-β1 produced a marginal elevation (non-significant) …
WebNov 30, 2024 · By contrast, the Smad3 protein level showed no significant change among the different groups (Fig. 5c). As a result, the promotion of MSC osteogenesis is mainly mediated by activation of the BMP2 ... how do i share my word documentWebSep 1, 2024 · TGF-β1 causes cardiac fibrosis by stimulating Smad3 and PI3K-Akt-GSK-3β signaling pathways. TGF-β1 phosphorylates and activates the highly-conserved cytoplasmic proteins of the SMADs family, and PI3K-Akt-GSK-3β pathway, thereby regulating the expression of the related genes leading to fibrosis. how do i share my wireless printerWebOct 2, 2024 · However, the importance of TGF-β-Smad2/3 signaling in fibroblast-mediated cardiac fibrosis has not been directly evaluated in vivo. Here, we examined pressure overload-induced cardiac fibrosis in fibroblast- and myofibroblast-specific inducible Cre-expressing mouse lines with selective deletion of the TGF-β receptors Tgfbr1/2, Smad2, … how do i share my zoom accountWebFeb 12, 2024 · RIP analysis showed that Smad3, but not Smad2/4, directly bound Crnde (Fig. 4B). Most interestingly, there was no change in the effect of Crnde on Smad3 protein and phosphorylation in TGFβ-induced myofibroblast differentiation (Fig. 4C,D). It is known that Smad3 binds to the promoter region of Acta2 to regulate the expression of α-SMA … how do i share office 365 to another computerWebJul 5, 2024 · Pin1 depletion restored Smad3 protein levels and tumor-suppressive activity, suggesting that the Pin1-Smad3 interaction has a negative impact on canonical Smad3 action. Collectively, the data show that the Pin1-Smad3 interaction, facilitated by CDK-mediated Smad3 phosphorylation, is associated with oncogenic TGFβ signaling and … how much money to live in mexicoWebApr 6, 2024 · After his tour in Germany, Fenderson was assigned to 1st Bn., 30th IR, 3rd ID, where he served as a Rifle Team leader, BFV Gunner, Rifle Squad leader and Company Master Gunner, and deployed to Egypt in support of Operation Bright Star. Fenderson was then assigned to the New York City Recruiting Bn., Queens Company, where he served … how much money to live comfortably in nycWebMonoclonal Antibody for studying CD3epsilon. Cited in 9 publications. Validated for Western Blotting, Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, CD3ε (CD3-12) Rat Monoclonal Antibody (CST #4443) is ready to ship. how do i share notes on iphone