Webb.fas/fasl途径 c.aicd途径 d.被动细胞死亡途径 ... 的杀伤的特点是. a.需识别靶细胞表面的抗原 b.具有mhci类限制性 c.不需mac参与 d.杀伤由ctl释放穿孔素及颗粒酶介导 ... In phase two, the now functional effector CTLs destroy the target cells. This can be done in two ways. These pathways are the cytotoxic protein pathway and the Fas ligand pathway. Apoptosis is the primary mechanism for both of these pathways. One pathway is the cytotoxic protein pathway. In this pathway perforins and granzymes are taken up by the target cell. In this pathway, the perforins facilitate the entry of granule contents into th…
IMMUNO CH. 13 Flashcards Quizlet
WebThe association of intracellular FasL with two populations of LGs, as documented in NK cells , may account for these discrepancies. FasL is targeted to MVB, where it localises together with APO2L/TRAIL both at the limiting membrane and in CD63 + intraluminal vesicles (ILV) that are released into the synaptic cleft as EVs (8, 9, 48, 54). WebStudy with Quizlet and memorize flashcards containing terms like 1. What is the effector molecule of humoral immunity? A. Antibodies B. Cytotoxic T cells C. Dendritic cells D. Helper T cells E. Plasma cells, 2. The role of cell-mediated immunity is: A. to find cells infected with intracellular pathogens. B. to find and eliminate cells infected with … bishop ullathorne knowledge organiser
CTL杀伤靶细胞可通过() - 答案库
WebExpert Answer. 1-a. The CTL would not kill the target cell - TCR (T-cell receptor) expressed by CTL (cytotoxic T-lymphocyte) recognizes the MHC: antigen complex presented by the target cell. If the TCR does not recognize the MHC: antigen complex, the CTL would not be able to bind to the target cell and therefore would not be able to kill it. Web-CTL help TH2-B cell help CD8+-CTLs. Properties of Effector T Cells ... -Fas ligand found on cell surface of CTL-FasL binds to Fas expressed on target cells and Fas signaling induces apoptosis in that cell. Perforin/Granzyme pathway. 24-48 hours after activation, CD8+ T cells produce granules containing: WebAug 15, 2007 · CTL lyse target cells through the release of cytolytic granule contents and cell surface expression of Fas ligand (FasL). Current models suggest that FasL is stored … dark tomorrow