WebThe only patient who did not respond to the single 6-mg rasburicase dose was a morbidly obese man (259 kg, body mass index 87 kg/m2) who subsequently responded to an additional dose of rasburicase 12 mg. These results warrant further investigation of a single 6-mg dose of rasburicase in adults with TLS or at high-risk for developing TLS. WebThe single fixed dose ranged from 0·05 mg/kg to 0·20 mg/kg. The pooled response data for the single dose of rasburicase showed that a single fixed dose was as effective as the prolonged rasburicase treatment …
Effectiveness of a single fixed dose of rasburicase 3 …
Web12. Liu CY1, Sims-McCallum RP et al. A single dose of rasburicase is sufficient for the treatment of hyperuricemia in patients receiving chemotherapy. Leuk Res. 2005 Apr;29(4):463-5.Epub 2004 Dec8. 13. Trifilio S, Gordon L, Singhal S et al. Reduced-dose rasburicase (recombinant xanthine oxidase) in adult cancer patients with hyperuricemia. WebFeb 8, 2024 · Rasburicase: recombinant uricase that catalyzes the breakdown of uric acid to allantoin Indications and dosing Treatment of established TLS: rasburicase infusion . Prophylaxis for intermediate to high-risk patients: rasburicase infusion OR single fixed-dose rasburicase G6PD deficiency hemolytic anemia Urinary alkalinization how much is the human life worth
Rasburicase injection - Queensland Health
WebRasburicase injection is used to treat high levels of uric acid (a natural substance that builds up in the blood as tumors break down) in people with certain types of cancer who … WebJun 1, 2011 · It is concluded that a single 3-mg dose of rasburicase, used with close monitoring, is sufficient to treat most adults with uric acid levels up to 12 mg/dL, and continues to decline beyond 24 h in most patients without additional treatment. Rasburicase was administered at a fixed dose of 3 mg to treat 287 episodes of elevated serum uric … WebA single, fixed dose of rasburicase (6 mg maximum) for treatment of tumor lysis syndrome in adults A single, fixed dose of rasburicase (6 mg maximum) for treatment of tumor lysis syndrome in adults Eur J Haematol. 2010 Aug;85 (2):177-9. doi: 10.1111/j.1600-0609.2010.01457.x. Epub 2010 Apr 12. Authors Miriam Giraldez , Katarzyna Puto PMID: … how much is the hummer ev going to cost