WebOct 30, 2012 · In order to preserve genome integrity, extrinsic or intrinsic DNA damages must be repaired before they accumulate in cells and trigger other mutations and genome rearrangements. Eukaryotic cells are able to respond to different genotoxic stresses as well as to single DNA double strand breaks (DSBs), suggesting highly sensitive and robust … WebThese mechanisms of DNA repair can be divided into two general classes: (1) direct reversal of the chemical reaction responsible for DNA damage, and (2) removal of the damaged bases followed by their replacement …
How do thermophiles keep their DNA intact? : r/askscience - Reddit
WebRepair processes that help fix damaged DNA include: Direct reversal: Some DNA-damaging chemical reactions can be directly "undone" by enzymes in the cell. Excision repair: Damage to one or a few bases of DNA is often fixed by removal (excision) and replacement of the … WebOct 20, 2005 · The majority of these proteins (17 of 31) are encoded in the TT megaplasmid and 11 belong to the predicted mobile DNA repair system characteristic of thermophiles [16, 45] (Figure 7A; see details below). In addition, TT has acquired 4 "archaeal" genes that are not encoded in any of the genomes of mesophilic bacteria assigned to COGs (peptide ... how to separate the alphabet for filing
Thermophile - Wikipedia
WebSep 1, 2003 · The X‐ray structure of the 19 kDa C‐terminal domain of the Escherichia coli ada gene product is reported, the prototype of suicidal methyltransferases, where the active site cysteine is buried and a model for the significant conformational change that the protein must undergo in order to bind DNA and effect methyl transfer is proposed. WebOct 7, 2024 · Blue Green Algae, (Cyanobacteria), is one of four thermophiles that has adapted to thrive in the extreme temperatures of our Hot Springs, (Average 143° F, 62° C). ... enzymes in thermophiles are more resilient because they are packed very tightly and held by especially strong links.The DNA of thermophiles is adapted to life at high ... Web2. Thermophiles typically possess lipids rich in saturated fatty acids in their cytoplasmic membranes thus allowing the membranes to remain stable and functional at high … how to separate the date in excel