Phlpp2 scilencing rna

Author: aulf

August undefined, 2024

Webb4 okt. 2024 · Silencing PHLPP2 protein expression prolongs the survival of leukemia cells subjected to severe glucose limitation by promoting a switch to AMPK-mediated fatty …

PHLPP2 transcriptomics data - The Human Protein Atlas

Webb1 dec. 2024 · PHLPP2 expression was highly upregulated in hypoxia-injured cardiomyocytes. Inhibition of PHLPP2 by small interfering RNA (siRNA)-mediated gene … Webb2 sep. 2013 · Conversely, RNA interference–mediated silencing of endogenous miR-205 abrogated these effects. The malignant properties induced by miR-205 in NSCLC cells … cshidworld cordless hair clippers

Loss of pleckstrin homology domain and leucine-rich repeat …

WebbMoreover, silencing of PHLPP2 and FOXO4 mimicked the tumor-promotive effects of miR-762 on HNSCC cells. Notably, overexpression of PHLPP2 and FOXO4 abolished the pro-tumoral function of miR-762 on cell proliferation and migration. Conclusion: miR-762 promotes HNSCC progression by targeting PHLPP2 and FOXO4. WebbWhen both PHLPP1 and PHLPP2 are knocked down using siRNA and cells are stimulated using epidermal growth factor, peak Akt phosphorylation at both Serine473 and … WebbPHLPP2 deletion in mouse endothelium results in decreased neo-intima formation following vascular injury, indicating that the prevention of AKT1 overactivation by … cshidworld led lights

Hongliang Guo 1 Publications 28 Citations Related Authors

The Phosphatase PHLPP2 Plays a Key Role in the Regulation of

WebbRNA crosslink immunoprecipitation, quantitative reverse transcriptase-PCR (qRT-PCR) and immunoblot experiments demonstrated direct interaction of miR-217 with kallikrein 7 … Webb30 sep. 2024 · PHLPP2 exhibited downregulated expression in human NSCLC tissues. GEPIA was used to detect PHLPP2 mRNA levels in different carcinomas. 25 We first … eager waitingWebbRNA Secondary Structure: Associated Diseases: Mature miRNA Information; Mature miRNA: hsa-miR-92b-3p: ... anti-silencing function 1B histone chaperone: 1: 1: … cshidworld bluetooth 5.0 earbuds

"WebbThey are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing. For … " - Phlpp2 scilencing rna

Phlpp2 scilencing rna

PHLPP2 transcriptomics data - The Human Protein Atlas

Webb7 juli 2024 · PHLPP2, a target of miR-141 and miR-424, was downregulated in colon cancer. PHLPP2 upregulation and miR-141 and miR-424 downregulation suppressed the colon … WebbPrice & Turnaround time of PHLPP2 SAM guide RNA $199.00 for each SAM gRNA sequence synthesized and cloned into the pLenti_sgRNA(MS2)_zeo vector $50.00 each …

Did you know?

Webb21 mars 2024 · PHLPP2 (PH Domain And Leucine Rich Repeat Protein Phosphatase 2) is a Protein Coding gene. Diseases associated with PHLPP2 include Optic Atrophy 8 . … Webb1 juni 2009 · PHLPP2 overexpression increases apoptosis in cancer cell lines under low serum conditions; this effect is partially blocked by overexpressing an Akt mutant that is …

Webb27 mars 2014 · A 15-nM concentration of small interfering RNA (siRNA) targeting PHLPP2, which produced nearly 60–70% knockdown after 48 h incubation (Supplementary Figure … WebbRNA silencing or RNA interference refers to a family of gene silencing effects by which gene expression is negatively regulated by non-coding RNAs such as microRNAs.RNA …

Webb1 dec. 2024 · Interestingly, PHLPP2 inhibition mediated by small interfering RNA (siRNA) knockdown significantly improved cell viability and downregulated apoptosis and … Webb1 dec. 2024 · In the last two decades, numerous studies have revealed that non-coding RNA (ncRNA), such as microRNA (miRNA), long non-coding RNA (lncRNA), circular RNA (circRNA), small interfering RNA (siRNA), and RNA interacting with piwi proteins (piRNA), are crucial regulators of gene expression.

Webb1 dec. 2024 · Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs more than 200 nucleotides in length. LncRNAs can act as competing endogenous RNA (ceRNA) …

WebbRNA Secondary Structure: Associated Diseases: Mature miRNA Information; Mature miRNA: hsa-miR-92b-3p: ... anti-silencing function 1B histone chaperone: 1: 1: MIRT040667: RRP1: ribosomal RNA processing 1: 1: 1: MIRT040668: TNPO2: transportin 2: 1: 1: ... PHLPP2: PH domain and leucine rich repeat protein phosphatase 2: 2: 5: eages30Webb8 dec. 2024 · two PHLPP isozymes, PHLPP1 and PHLPP2, were identified in a search for phosphatases that dephosphorylate Akt, and thus suppress growth factor signaling. … cshidworld led motion sensor lightWebb22 nov. 2024 · RNA-induced silencing complex (RISC) is a 200–500 kDa multiprotein effector complex that has endonuclease activity and integrates mature miRNA. Then, … cshidworld led sensor lightingWebbRNA binding motif protein 43;alpha-2-macroglobulin like 1;dermatan sulfate epimerase-like ... synaptotagmin like 1;major facilitator superfamily domain containing 13A;zinc finger … eager womanWebbFor example, MIR2911, a plant 26S ribosomal RNA-derived small RNA, exhibited high stability against RNases and strong stability in circulation[Citation 150]. However, many … eager wantWebb7 maj 2024 · We also show that silencing ... the PHLPP1 and the PHLPP2 immunoblots contained gel splices. Lane 3 of the Cdk2 immunoblot from Fig. 1C depicted results from … eager white sherwin williamsWebbLong noncoding RNA SNHG6 promotes the progression of colorectal cancer through sponging miR-760 and activation of FOXC1 Yuekun Zhu,1,* Yanwei Xing,1,* Fengxu Chi,1 … eager young minds of tomorrow