Phosphine toxicity
http://www.fao.org/3/x5042e/x5042E0a.htm#:~:text=Phosphine%20is%20very%20toxic%20to%20all%20forms%20of,the%20gas%20is%20not%20absorbed%20through%20the%20skin. WebJan 25, 2024 · Because phosphine toxicity is based on oxidative respiration, the involvement of energy metabolism in phosphine toxicity/resistance was hypothesized [30,42,43,44]. Phosphine’s action of generating oxygen-derived free radicals, leading to cellular damage, appears to be one of the important factors associated with phosphine toxicity in insects.
Phosphine toxicity
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WebResults of studies show that phosphine gas is highly toxic by the inhalation route. Considering the use patterns and chemical characteristics, the other acute toxicity data … WebAcute toxicity occurs primarily by the inhalation route when aluminum phosphide decomposes into the toxic gas, phosphine. The human median lethal dose for aluminum phosphide has been reported to be 20 mg/kg. Rated as super toxic: probable oral lethal dose is less than 5 mg/kg or less than 7 drops for a 70 kg (150 lb.) person. (EPA, 1998)
WebChemical Classification: Warfare and Terrorism Agents (used in acts of war or terror) Summary: Phosphine is a colorless, flammable, and explosive gas at ambient … WebPhosphine 7803-51-2 Hazard Summary Phosphine is used as an insecticide for the fumigation of grains, animal feed, and leaf-stored tobacco. Acute (short-term) inhalation …
WebNational Center for Biotechnology Information WebPhosphine is a multisystem toxicant that can cause pulmonary irritation, CNS depression, and cardiovascular collapse. There is no antidote for phosphine poisoning. Treatment …
WebToxicity of phosphine is related to oxidant free radicals and associated inhibition of enzymes of metabolism, such as cytochrome c oxidase. 8 Apart from supportive treatment, novel therapies such as N -acetylcysteine, replenishing cellular glutathione, and magnesium, which has been reported to have antioxidant properties, have been suggested. 9 A …
WebNov 12, 2007 · Phosphine is toxic toward all actively aerobically respiring organisms. In this report, we chose to examine the toxic effects of phosphine in vivo in the model organism C. elegans. This nematode is ideal for studying fumigant toxicology, particularly because of its tremendous reproductive capacity and rapid life cycle, which facilitates toxin ... bky66.comWebPhosphine is acutely toxic; exposure to high levels cause immediate effects Early symptoms of acute phosphine or phosphide exposure are non-specific and include respiratory … bky61 comWebFeb 1, 2006 · Phosphine Toxicity: Ethical Questions. In their article McDaniel et al. (2005) presented three case studies, one involving an evaluation by Sciences International, Inc. ( Pepelko et al. 2004 ), of which I am the president and CEO. This case study was related to the reregistration of phosphine by the U.S. Environmental Protection Agency (EPA). daughter smoking storyWebphosphine and zinc salts. Hydrolysis of metal phosphides on the skin could lead to the evolution of gaseous phosphine, which can then be absorbed by inhalation. Little percutaneous absorption of metal phosphides occurs. Phosphine inhibits the cytochrome oxidase. The organs with the greatest oxygen requirements will be the most sensitive to … bky67.combky51.comPhosphine is a highly toxic respiratory poison, and is immediately dangerous to life or health at 50 ppm. Phosphine has a trigonal pyramidal structure. Phosphines are compounds that include PH 3 and the organophosphines, which are derived from PH 3 by substituting one or more hydrogen atoms with organic groups. See more Phosphine (IUPAC name: phosphane) is a colorless, flammable, highly toxic compound with the chemical formula PH3, classed as a pnictogen hydride. Pure phosphine is odorless, but technical grade samples have a highly See more Philippe Gengembre (1764–1838), a student of Lavoisier, first obtained phosphine in 1783 by heating white phosphorus in … See more Phosphine may be prepared in a variety of ways. Industrially it can be made by the reaction of white phosphorus with sodium or potassium hydroxide, … See more Deaths have resulted from accidental exposure to fumigation materials containing aluminium phosphide or phosphine. It can be absorbed either by inhalation See more PH3 is a trigonal pyramidal molecule with C3v molecular symmetry. The length of the P−H bond is 1.42 Å, the H−P−H bond angles are 93.5°. The dipole moment is 0.58 D, which increases with substitution of methyl groups in the series: CH3PH2, 1.10 D; (CH3)2PH, 1.23 D; … See more Organophosphorus chemistry Phosphine is a precursor to many organophosphorus compounds. It reacts with formaldehyde … See more • Diphosphane, H2P−PH2, simplified to P2H4 • Diphosphene, HP=PH See more bky 61.comWebPhosphine is a poisonous gas that can make you sick and can even lead to death. Learn how you might come in contact with phosphine and how you can protect your health. What is … daughter smoking newport\u0027s