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Phospho-sting-s365

WebJan 13, 2024 · This novel vector, STINGPOX, produces cyclic di-AMP, a STING agonist, which drives IFN signaling critical to the anti-tumor immune response. We demonstrate that STINGPOX can drive IFN signaling in primary human cancer tissue explants. WebAntibodies against p-STING (S365), p-IRF3 (S396), p-IκBα (S32), p-TBK1 (S172), p-STAT1 (Y701), p-NF-κB p65 (S536), p-IKKε (S172), LC3A/B, and GAPDH were from Cell Signaling; …

Phospho-STING (Ser366) Polyclonal Antibody (PA5-105674)

WebPhospho-STING (Ser365) Antibody (PA5-117271) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser365) Polyclonal Antibody (Product # PA5-117271). … great smoky mountains loop https://eliastrutture.com

Phospho-STING (Ser365) Polyclonal Antibody - Thermo …

WebCell Signaling Technology's Phospho-STING (Ser365) (D8F4W) Rabbit mAb is a Rabbit monoclonal antibody. The Phospho-STING (Ser365) (D8F4W) Rabbit mAb Antibody was generated using stimulator of interferon response cGAMP interactor 1, and STING1 as the antigen. It reacts with Mouse. This antibody has been shown to work in applications such … WebWhole cell lysates were analyzed by WB for phospho-STING (p-STING S365), STING, phospho-TBK1 (p-TBK1 S172), TBK1, phospho-IRF3 (p-IRF3 S396), IRF3, IFIT1, cGAS and FLAG (for disA expression). β-actin levels were used as loading control. Data are representative of three independent experiments. WebOct 24, 2013 · We conclude that phosphorylation of S366 (S365 in murine STING) occurs after autophagy and may negatively regulate STING activity to prevent sustained type I IFN production following activation by cytosolic dsDNA. ... 39-2700, used for murine IRF3); anti-IRF3 (Santa Cruz Biotechnology, sc-9082); anti-phospho-IRF3 (Cell Signaling, 4947); anti ... great smoky mountains maggie valley

STING regulates BCR signaling in normal and malignant B

Category:Anti-Phospho-STING-S365 antibody produced in rabbit

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Phospho-sting-s365

Phospho-STING (Ser366) Polyclonal Antibody (PA5-105674)

WebSep 30, 2024 · A polyclonal antibody against phospho-S365 of mouse STING was generated in rabbits and affinity-purified (Fig. S2E). Polyclonal antibodies against mouse STING, Igα, … WebMonoclonal Antibody for studying STING (Ser366) phosphate. Cited in 20 publications. Validated for WB, IP, IF, F. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-STING (Ser366) (E9A9K) …

Phospho-sting-s365

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WebAnti-Phospho-STING-Ser366 antibody (STJ194750) Polyclonal Host : Rabbit Applications : WB Reactivity : Human, Rat, Mouse £42.00 - £189.00 View Options Anti-STING/TMEM173 antibody (332-342) (STJ503146) Clonality : Polyclonal Host : Rabbit Applications : ELISA, IP, WB Reactivity : Human, Mouse, Rat £380.50 View Options WebJun 3, 2024 · In clones in which VPS13C protein expression had been successfully restored, phospho-STING and phospho-TBK1 were restored to WT ... cat# 19781, …

WebSTING is a four transmembrane (a.a. 21-41, 47-67, 87-106, 116-136) protein with both its N- and C-terminal ends exposed intracellularly (a.a. 1-20 and 137-379).The C-terminal cytoplasmic tail contains the c-di-GMP-binding domain (CBD; a.a. 153-340) with two c-di-GMP-binding regions (a.a. 162-167 & 238-241). Spécificité WebSTING is a four transmembrane (a.a. 21-41, 47-67, 87-106, 116-136) protein with both its N- and C-terminal ends exposed intracellularly (a.a. 1-20 and 137-379).The C-terminal cytoplasmic tail contains the c-di-GMP-binding domain (CBD; a.a. 153-340) with two c-di-GMP-binding regions (a.a. 162-167 & 238-241). 特異性

WebWhole cell lysates were analyzed by WB for phospho-STING (p-STING S365), STING, phospho-TBK1 (p-TBK1 S172), TBK1, phospho-IRF3 (p-IRF3 S396), IRF3, IFIT1, cGAS and FLAG (for disA expression). β-actin levels were used as loading control. Data are representative of three independent experiments. WebPhospho-B-Raf (Ser445) Antibody detects endogenous levels of B-Raf when phosphorylated at serine 445. Species Reactivity: Human, Mouse, Rat, Monkey Species predicted to react based on 100% sequence homology:

WebJul 7, 2024 · To initiate signaling, serine 365 (S365) in the C-terminal tail (CTT) of STING is phosphorylated, leading to induction of type I interferons (IFNs). Additionally, evolutionary …

Webphospho irf 3 ser396 / stars Cell Signaling Technology Inc p irf3 P Irf3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more Average Price from $ 2024-04 / stars Cell Signaling Technology Inc great smoky mountains name originWebHTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry. great smoky mountains naWebJan 13, 2024 · We apply CARVE to rapidly generate a novel immunogenic vaccinia virus vector, which expresses a bacterial diadenylate cyclase. This novel vector, STINGPOX, produces cyclic di-AMP, a STING... florange thionvilleWebRabbit Phospho-STING-S365 Rabbit pAb (AP1199), validaed in WB and tested in Human,, Mouse. 100% Guaranteed. ABclonal provides trial size antibody samples for target … great smoky mountains moonshineWebPhospho-STING (Ser366) Antibody recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. great smoky mountains mugWebPhospho-S365 acts as a docking site for IRF3, a transcription factor that is phosphorylated and activated by TBK1, leading to transcriptional induction of type I interferons (IFNs). great smoky mountains murderWebMay 22, 2024 · Macrophage-stimulator of interferon genes (STING) signaling mediated sterile inflammation has been implicated in various age-related diseases. However, whether and how macrophage mitochondrial DNA (mtDNA) regulates STING signaling in aged macrophages remains largely unknown. great smoky mountains luxury cabins