WebMay 15, 2024 · Shwachman-Diamond syndrome (SDS) is a rare autosomal recessive disorder characterized by bone marrow failure (BMF; cytopenia or aplastic anemia), exocrine pancreatic insufficiency, and skeletal abnormalities, with a predisposition to myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML) [1]. Although most individuals … WebApr 1, 2002 · IN 1964 Harry Shwachman together with Louis Diamond, Frank Oski, and Kon-T Khaw first described the syndrome of pancreatic insufficiency and bone marrow dysfunction, now commonly known as the Shwachman-Diamond syndrome (SDS). 58 They observed five children with neutropenia and pancreatic insufficiency which was not part …
Hematopoietic Stem Cell Transplantation for Shwachman-Diamond Syndrome …
WebShwachman-Diamond syndrome (SDS) is characterized by: exocrine pancreatic dysfunction with malabsorption, malnutrition, and growth failure; hematologic abnormalities with single- or multilineage cytopenias and susceptibility to myelodysplasia syndrome (MDS) and acute myelogeneous leukemia (AML); and bone abnormalities. In almost all affected children, … WebJan 24, 2011 · To investigate the cognitive, behavioral and adaptive functioning of children with Shwachman-Diamond syndrome (SDS). Thirty-two children with SDS (6-17 years) were evaluated by use of standardized ... reactive chemicals
Shwachman-Diamond syndrome - About the Disease
Web- Extracted and reported patient data into a national, multi-center, pediatric research registry for patients with Shwachman-Diamond Syndrome (SDS), myelodysplastic syndrome (MDS), and acute ... WebTo analyze the different clinical manifestations and genetic characteristics of Shwachman diamond syndrome in a female patient aged 1 month and 24 days. ... Wang G, et al. … WebOct 18, 2024 · Clinical characteristics: Shwachman-Diamond syndrome (SDS) is characterized by: exocrine pancreatic dysfunction with malabsorption, malnutrition, and growth failure; hematologic abnormalities with single- or multilineage cytopenias and susceptibility to myelodysplasia syndrome (MDS) and acute myelogeneous leukemia … reactive chart