Siglec 10 antibody
WebJul 4, 2014 · Siglec-10 (human homolog of mouse Siglec-G) was detected on all B cells and also subsets of human leukocytes including eosinophils, monocytes and a minor … WebSIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition …
Siglec 10 antibody
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WebThe 5G6 monoclonal antibody specifically recognizes Sialic acid-binding Ig-like lectin 10 (Siglec-10). Siglec-10 is a type I transmembrane glycoprotein encoded by SIGLEC10 …
WebApr 10, 2024 · The Siglec-Fc protein, a fusion protein combining Siglec with the Fc part of a human antibody, is a promising sialic acid-Siglec axis-targeted agent for cancer treatment … WebJul 17, 2024 · Blocking the interaction between CD24 and Siglec-10 with a monoclonal antibody can robustly augment the phagocytosis of human tumors expressing CD24 . Other. CD24 on the surface of tumor cells can …
Websialic acid binding Ig like lectin 10 , PRO940 , SIGLEC-10 , SLG2 ... WB analysis of OVCAR-3 cells using GTX45910 SIGLEC10 antibody at 0.2-1μg/ml. REFERENCE. There are currently … WebBuy rabbit polyclonal antibody to SIGLEC10 (A54002). Applications: ELISA, IP and WB. Reactivity: Human and Rat. ️ Low Prices ️ 100% Guarantee. Useful Links. 01223 298 ...
Like most but not all other Siglecs, Siglec-10 bears an ITIM (Immunoreceptor tyrosine-based inhibitory motif) within its cytoplasmic domain. Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to … See more Sialic acid-binding Ig-like lectin 10 is a protein that in humans is encoded by the SIGLEC10 gene. Siglec-G is often referred to as the murine paralog of human Siglec-10 See more SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor … See more • Li N, Zhang W, Wan T, et al. (2001). "Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells". J. Biol. Chem. 276 (30): 28106–12. doi:10.1074/jbc.M100467200. PMID 11358961. See more
WebSIGLEC 10 antibody. Siglec G antibody. Siglec-like protein 2 antibody. SIGLEC10 antibody. Siglecg antibody. SLG2 antibody : Protein information supplied by UniProt . Accessories. … try hyland.comWebTested in Western Blot (WB), Immunoprecipitation (IP) and ELISA (ELISA) applications. This antibody reacts with Human, Rat samples. Supplied as 200 µL purified antibody (0.5-1.5 … philkesselmayer2021 outlook.comWebSiglec-15, which selectively drives immunosuppression in the tumor microenvironment, has emerged as a viable therapeutic target. In a phase I trial of NC318, a Siglec-15 antibody, … try i canon them组连词成句WebNov 10, 2024 · AK007 is a humanized Siglec-10 antagonist antibody designed to block Siglec-10 interaction with all known ligands (CD24, CD52, and VAP-1). By targeting Siglec … try ibex tumblerWebRabbit Polyclonal Anti-SIGLEC10 Antibody against Human sialic acid binding Ig-like lectin 10. Antibody validation: Validated for Immunohistochemistry and Western Blot. Support; … try hyoWebNov 29, 2024 · Summary. Siglec-9 is an immune checkpoint target and an immunoinhibitory receptor that can engage either sialic acid ligands or agonistic antibodies. Through Siglec-9 sialic acid interactions, activated immunoreceptor tyrosine-based inhibitory signaling of the immune cells can lead to unfavorable immunosuppression. try hylandWebSiglec-10 is a sialic acid-binding Ig-like lectin that has been shown to negatively regulate innate and adaptive immune system function (1). Siglec-10 is a type 1 transmembrane … try hypnosis