Thiol-modifier-c6-s-s cep
WebFigure 1. Example disulfide bond reduction of a 5'-Thiol-Modifier C6 S-S oligonucleotide. Thiol-modified oligonucleotides are shipped in disulfide form to prevent spontaneous, uncontrolled oxidation, which in turn would lead to dimer formation, thereby rendering the oligonucleotide useless. WebThe final category for cleavable linkers is disulfides. Disulfides are readily cleaved by reducing agents such as dithiothreitol (DTT) or tris(2-carboxyethyl)phosphine (TCEP) to release free sulfhydryl groups (Figure 1E). This would typically be accomplished with Thiol-Modifier C6 S-S, but all other disulfide linkages would also be applicable.
Thiol-modifier-c6-s-s cep
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WebA primary amino group or a thiol group can be used to attach a variety of modifiers (such as fluorescent dyes) to an oligonucleotide or used to attach an oligonucleotide to a solid surface. Label Name. Purifications. Positions. Price (2OD) Price (5OD) Price (10OD) 5’-Amino-Modifier-C6. HPLC. WebThiol-Modifier-C 6-S-S Cep; 5'-Thiol Modifier C6 S-S; Sort by. Lower prices first. Higher prices first. Lower purities first. Higher purities first. Faster estimated delivery first. See more categories . This search does not contain any category. ... Thiol-modifier c6 S-S is a useful research chemical. Buy high-quality Thiol-modifier c6 S-S ...
WebAdd Thiol-Modifier C6 S-S to any nucleoside support or use Thiol-Modifier C3 S-S CPG to synthesize the desired oligonucleotide. To the standard ammonium hydroxide used for deprotection, add dithiothreitol (DTT) to a concentration of 0.05M. Carry out deprotection at 55°C for 16h. This procedure removes the base protecting groups and cleaves the ... WebAt OEM by QIAGEN, we enable our OEM partners to benefit from economies of scale, combined with the knowledge that there is no compromise on the quality of OEM oligonucleotides we provide. We are capable of incorporating a large selection of modifications in oligonucleotide development and manufacturing, according to GMP …
Web8 rows · 5' Thiol Modifier C6 S-S Return to Attachment Chemistry / Linkers Modifications. Thiol Modifications. Scientific Details. MW: 328.4: Mod Code: /5ThioMC6-D/ Pricing …
WebItem Thiol-Modifier C6 S-S; Company BOC Sciences; Price Supplier Page View Company Product Page; Catalog Number 148254-21-1; Purity >95% by HPLC; Molecular Weight …
Web5' Thiol Modifier C6 S-S Return to Attachment Chemistry / Linkers Modifications. Thiol Modifications. Scientific Details. MW: 328.4: Mod Code: /5ThioMC6-D/ Pricing Details. Product Pricing Order; 100 nmole DNA Oligo: $153.70 USD: Add To Order: 250 nmole DNA Oligo: $153.70 USD: Add To Order: 1 umole DNA Oligo: $238.50 USD: Add To Order: how to lower amylase levelWebThiol-Modifier C6 S-S CE Phosphoramidite; Molecular formula: C 42 H 61 N 2 O 5 PS 2: Cat. No. 14-0100-XX: M.W. 769.05: F.W. Unreducesd:328.42 Reduced:196.20: HPLC ³¹P NMR … how to lower a model a chassisWebApr 11, 2012 · The amino-modifier 5’ Amino Modifier C6 with a spacer arm of 7 atoms (6 carbon and 1 nitrogen) is the simplest choice. 5’ Amino Modifier C12 increases the distance between the functional amine and the DNA sequence. Amino Modifier dT inserts the functionality internally from an added dT base while the Uni‑Link™ Amino Modifier does … how to lower androgen levels